I have tried many different supplements over the years for various things, but MSM is the one that I cannot go without; the one that if I had to give up everything I was taking and could only take one thing, this would be it. I initially started taking this for some skin concerns I was having a while back, which cleared up several months after consistent use, but I soon realized all the additional benefits I was receiving as well. The energy and mental focus alone is worth it. But also my hair and nails are healthier, and I don't find my body aches like it used to either. I take this in the morning and late afternoon. When I travel I take the MSM capsules which are amazingly convenient in their own right. I've tried a handful of MSM brands and always found myself coming back to No Boundaries. I truly think they have the best product out there. It's pure, organic, shipping is fast, and their customer service is on point.